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Could Certain Fatty Foods Be Linked to Aggressive Prostate Cancer?

FRIDAY, April 22, 2016 (HealthDay News) — What men eat — particularly fatty meats and cheese — may affect how quickly their prostate cancer progresses, a new study suggests.

“We show that high dietary saturated fat content is associated with increased prostate cancer aggressiveness,” said study author Emma Allott, a research assistant professor at the Gillings School of Global Public Health at the University of North Carolina.

“This may suggest that limiting dietary saturated fat content, which we know is important for overall health and cardiovascular disease prevention, may also have a role in prostate cancer,” she said in a school news release.

However, the study did not prove that diet directly affects prostate cancer behavior, only that there is a link between those factors.

The researchers looked at more than 1,800 men from North Carolina and Louisiana. All had been diagnosed with prostate cancer between 2004 and 2009. They were asked about their eating habits and other factors at the time of their diagnosis.

Higher intake of saturated fat from foods such as fatty beef and cheese was linked with more aggressive prostate cancer, the researchers found.

A diet high in saturated fat contributes to higher cholesterol levels, researchers said. They noted that the link between saturated fat and aggressive prostate cancer was weaker in men who took cholesterol-lowering statin drugs.

The researchers said that suggests that statins reduce, but don’t completely reverse, the effect that high amounts of saturated fat may have on prostate cancer.

The study also found that higher levels of polyunsaturated fats, found in foods such as fish and nuts, were associated with less aggressive prostate cancer.

Further research is needed to learn more about why a diet high in saturated fat is linked with more aggressive prostate cancer, Allott said.

The researchers presented their findings April 18 at the annual meeting of the American Association for Cancer Research in New Orleans. Findings presented at meetings are generally viewed as preliminary until they’ve been published in a peer-reviewed journal.

More information

The U.S. National Cancer Institute has more on prostate cancer.





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These Are the Genes Behind Healthy Aging

Photo: Getty Images

Photo: Getty Images

TIME-logo.jpg

Most studies about disease focus on people who are sick, since people with a disease are very likely to show whatever genetic or other biological changes are responsible for their condition.

But researchers are starting to find the flip side to that strategy attractive—studying people, rare though they might be, who have whatever changes are responsible for disease but somehow don’t get sick. Could they provide clues about how they’re able to overcome their biological condition and remain healthy despite being dealt a bad biological hand?

That’s the question that Dr. Eric Topol, director of the Scripps Translational Science Institute, and his colleagues wanted to investigate for healthy aging. While certain diseases such as heart problems, cancer, dementia and diabetes are more common with age, there are some people who remain remarkably immune to their effects and who are able to stay intellectually sharp and physically robust well into their 80s, 90s and even 100s. Topol and his team enrolled a group of these people they called the Wellderly: those older than 80 years with no chronic diseases and who did not take any medications for chronic illnesses. Of the 1,354 people in the study, 511 had their entire genomes sequenced, and over eight years, the researchers performed in-depth analysis of their DNA and compared their results to those from similarly aged people who did have the typical chronic diseases associated with aging.

RELATED: The Cure for Aging

To their surprise, Topol’s group reports in the journal Cell that it wasn’t genes associated with long life that set the Wellderly apart. In fact, there was little correlation between the genes that had already been identified as contributors to longevity and the genes that distinguish the Wellderly, who live long but are also relatively free of disease. “The healthy aging really seems to be a separate group that stay free of chronic disease versus the man-made long-lived person who may have a heavy chronic disease burden but is being kept alive with modern medicine,” says Topol. “We thought there would be a lot of overlap, but there wasn’t.”

What did set the Wellderly apart was a set of genes that related to their cognitive function. They were less likely to have the deleterious form of the ApoE gene that is linked to a higher risk of Alzheimer’s disease. They also found, however, that this group had higher rates of a rare variant of a gene that secretes proteins in the brain attracted to amyloid. Amyloid is the protein that builds up abnormally in the brains of Alzheimer’s patients, so this version of the gene is now an appealing target for some type of protective factor that may sponge up damaging amyloid before it causes Alzheimer’s. A drug that mimics the effects of this unusual form of the gene might be a way to help avoid Alzheimer’s.

RELATED: How to Live to 100: Researchers Find New Genetic Clues

But that’s just one way that people may be aging in good health. Topol says that it’s likely that for healthy aging, it’s necessary to both have genes that lower the risk of chronic diseases (such as avoiding the harmful form of ApoE) as well as having genes that confer some type of protection against the damaging effects of chronic illnesses (such as the newly identified and rare variant of the brain gene). “There are probably hundreds of protective variants,” he says.

What this study highlights is that the only way to identify them is to study people who age well, without disease, since some of the genetic contributions to their healthy state might be rare. It’s also important to conduct whole genome sequencing on these people to fully understand any useful clues their DNA may hold. “It’s like finding nature’s secrets to how people stay healthy,” says Topol. “Learning things from nature rather than mining libraries of molecules for potential healthy aging drugs seems like it can be highly constructive.”

This article originally appeared on Time.com.




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Dove’s New #LoveYourHair Campaign Celebrates Diversity in Beauty

Photo: Dove

Photo: Dove

It’s an exciting time for beauty diversity, with women standing up and taking action against the unrealistic standards we’ve lived under for decades where “beauty” was pigeon-holed into characteristics only a select few actually hold. Dove’s brand new #LoveYourHair campaign is the perfect example of how the movement is gaining traction with the important message that beautiful hair can include all textures, shades, lengths, and styles.

RELATED: Of Course, Gigi Hadid Looks Insanely Chic with Messy Hair

Shockingly, according to research stats from Dove, 3 in 4 women believe they would have more self-confidence if they felt like they weren’t being judged by their hair and a whopping 90 percent of women say they need to embrace their strands and quit comparing themselves to others. Sadly only 11 percent of women say they love everything about their hair and wouldn’t change a thing. These are numbers that have to change, and Dove’s #LoveYourHair campaign team members, like Me, My Hair, and I: Twenty-seven Women Untangle an Obsession author Elizabeth Benedict, are at the ready to champion that change.

“I’m thrilled to be part of the Love Your Hair campaign because it fits perfectly with what I’ve learned talking to women across the country about hair. We need to love our hair and ourselves more and those two things are intrinsically connected,” said Benedict.

RELATED: This Is Why Irina Shayk Looks Like with Short Hair

In the campaign film, a diverse group of women who are bucking the stereotypes of what hair they “should” have according to ridiculous societal pressures are featured wearing their locks exactly as they please…and they all look gorgeous.

Chances are if you watch the spot, you’ll totally be able to relate. Hopefully the film and the hashtag can give us all that little reminder to love ourselves just the way we are.

This article originally appeared on InStyle.com/MIMI.




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Painkiller Addiction Relapse More Likely for Some

FRIDAY, April 22, 2016 (HealthDay News) — Certain factors can help health care professionals predict who might relapse during treatment for prescription opioid painkiller addiction, Canadian researchers report.

Opioid abuse is a serious problem in Canada and the United States, the researchers said. Methadone treatment is the most common therapy. But, nearly half of patients continue to abuse opioids during or after methadone treatment, researchers noted.

Opioid painkillers include such drugs as Oxycontin, Percocet and Vicodin.

“We can improve our tailoring of treatment to each patient if we know who among patients taking methadone treatment is at high risk for opioid relapse,” said principal author Dr. Zena Samaan. Samaan is an associate professor of psychiatry and behavioral neurosciences at McMaster University in Hamilton, Ontario.

“As well, health care providers can target more aggressive therapies to those at high risk,” she added in a university news release.

This study included 250 adults from Ontario who had been on a methadone treatment for an average of four years. The researchers found that relapse was more common among certain groups of patients.

Injection drug users were more than twice as likely to relapse as those who didn’t inject drugs. There was a 10 percent higher risk of relapse for every year later in life that a person first began abusing opioids, the study revealed.

Researchers also found a 7 percent higher risk of relapse for each day people used tranquilizers in the previous month.

However, at least one factor was protective, the study said. Researchers found that the older the patient, the less likely they were to relapse.

Findings from the study were published recently in the journal Substance Abuse Research and Treatment.

More information

The U.S. National Institute on Drug Abuse has more about opioids.





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Businesses Should Be Mindful of Zika Danger to Workers CDC Says

By Dennis Thompson
HealthDay Reporter

FRIDAY, April 22, 2016 (HealthDay News) — Summer, mosquito season and the threat of Zika virus transmission is approaching, and federal health experts on Friday issued guidelines to help protect American workers from infection.

Infection during pregnancy with the mosquito-borne virus is known to cause a devastating birth defect known as microcephaly (abnormally small heads) in babies. It’s also thought that a man can transmit the Zika virus to his female partner during sex.

Most cases of the birth defect have been limited to Brazil, which has reported more than 5,000 suspected or confirmed cases. However, many experts worry that mosquitoes in the United States might soon carry the virus.

To help minimize the danger, the U.S. Centers for Disease Control and Prevention on Friday advised that businesses implement safeguards for workers. Many are the same as for the population generally: Reduce levels of standing water (where mosquitoes can breed), provide workers with insect repellent, and advise employees to wear long pants, long sleeves and hats (including anti-mosquito netting if deemed necessary).

But there were other advisories specific to business.

“If requested by a worker, consider reassigning workers who indicate they are or may become pregnant, or male workers who have a sexual partner who is or may become pregnant, to indoor tasks to reduce their risk of mosquito bites,” the CDC said in a news release.

As for travel protocols, “employers should consider allowing flexibility in required travel to areas with active Zika transmission for workers who are concerned about Zika virus exposure,” the agency said. Again, this is especially important for women who are or may become pregnant, or men with sexual partners who may become pregnant.

Finally, “even if they do not feel sick, travelers returning to the United States from an area with Zika should take steps to prevent mosquito bites for three weeks so they do not pass Zika to mosquitoes that could spread the virus to other people,” the CDC said.

The new guidelines are part of the unfolding story around the Zika virus. Earlier this month, U.S. health officials confirmed that Zika does, in fact, cause birth defects. And that’s engaged many of those experts in an unprecedented debate.

At issue: Should government health-care officials recommend that American women delay getting pregnant in regions of the country once the mosquito-borne virus becomes active there?

So far, the virus in U.S. territories has been limited to Puerto Rico, the Virgin Islands and American Samoa. But as mosquito season approaches, health experts have said they expect to see infections in Gulf Coast states such as Florida and Texas, as well as Hawaii.

According to The New York Times, some infectious-disease experts believe that avoiding pregnancy during the coming mosquito season is the only way to prevent the birth defect microcephaly, which can lead to abnormally small heads and brains.

But some women’s health specialists argue that the government “shouldn’t tell women what to do with their bodies,” the Times reported. Federal health officials have never suggested that all women in a region of the country avoid pregnancy. Moreover, the specialists say, most babies conceived during Zika epidemics in Latin America — where the virus has been most prevalent — have been born healthy, the newspaper said.

For now, the debate continues, with Dr. Tom Frieden, director of the U.S. Centers for Disease Control and Prevention, calling it “a very long conversation.”

“We do not have a recommendation to not become pregnant,” Frieden said. “We do recommend access to contraception,” he added, the Times reported.

Currently, federal health officials recommend that pregnant women avoid areas where Zika is being actively transmitted by mosquitoes. To date, most of the infections have occurred in Latin America and the Caribbean.

The CDC also recommends Zika testing for people potentially exposed to the virus and who have signs or symptoms of infection, typically a fever and rash. For now, that basically means people who have traveled to or lived in Latin America or the Caribbean.

On Friday, the CDC reported that as of April 20, 388 cases of travel-linked Zika virus disease have been confirmed in the 50 states, and so far no American has picked up the disease locally. Thirty-three of the cases occurred during a pregnancy and eight were thought to be sexually transmitted.

In an estimated 80 percent of cases of Zika infection, the symptoms are mild or the person may not even know they’ve been infected, according to health officials.

But, Zika also has been linked to Guillain-Barre syndrome, an uncommon nervous system illness in which a person’s immune system damages the nerve cells, causing muscle weakness and sometimes paralysis, according to the CDC.

Dr. Sonja Rasmussen is director of the CDC’s Division of Public Health Information and Dissemination. She said that the exact risk of brain-related birth defects to the baby of a mother infected with Zika is still unclear, because some Zika-infected women have given birth to apparently healthy babies.

“We don’t know if the risk is somewhere in the range of 1 percent or in the range of 30 percent,” she said. “That’s one of the key questions we really want to answer.”

Researchers also don’t know if Zika will wind up causing learning disabilities to these apparently healthy children later in life, or if Zika also causes birth defects beyond those that are brain-related, Rasmussen added.

Public health officials have said they expect Zika to become active in the United States with the onset of mosquito season. The Aedes aegypti mosquito is expected to be the primary carrier in the United States.

Gulf Coast states are most at risk for local transmission of Zika, CDC officials have said. However, the A. aegypti mosquito ranges as far north as San Francisco, Kansas City and New York City, although health officials have said infections that far north are unlikely.

More information

For more on Zika virus, visit the U.S. Centers for Disease Control and Prevention.

To see the CDC list of sites where Zika virus is active and may pose a threat to pregnant women, click here.





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4 Ways to Tell If You’re at a Healthy Weight

Illustration: Aad Goudappel

Illustration: Aad Goudappel

More than 54 million Americans who are labeled overweight or obese according to their body mass index (BMI), a weight-to-height ratio, are actually healthy, says a new study in the International Journal of Obesity. Wondering where you stand? Check into these digits instead.

RELATED: This Indiana Teen Explained to Her Teacher Why BMI Is Total BS

Waist circumference

If your belly is home to excess fat, you may be at greater risk of heart disease and type 2 diabetes. Wrap a tape measure around your middle just above your hip bones, at about your belly button. A healthy measurement for women is less than 35 inches.

Resting heart rate

Put two fingers over your pulse—at the wrist or neck—and count the number of beats in one minute. Between 60 and 100 beats is normal. A lower resting heart rate generally implies better physical health; a less active lifestyle can lead to a higher rate because the heart has to work harder.

RELATED: 13 Best (and Worst) Ways to Measure Body Fat

Body fat percentage

Unlike BMI, this number reveals the amount of excess fat, separate from muscle mass. A healthy range for women is 20 to 32 percent. Get a bioelectrical impedance analysis at your health club; a machine sends electricity through your body to calculate the amount of fat versus lean tissue.

Basal metabolic rate

BMR factors in your height, weight, gender, activity level and age to approximate the number of calories you burn while at rest; you can also use it to estimate how many calories to cut from your diet each day to achieve your weight-loss goal. Plug in your info at http://ift.tt/1SBkpJM.




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Let Safety Bloom in Your Garden This Season

FRIDAY, April 22, 2016 (HealthDay News) — Gardening offers exercise and fresh food, but don’t forget to protect yourself from potential hazards, the U.S. Centers for Disease Control and Prevention says.

Some of those dangers include: insects, too much sun, garden tools and chemicals, according to the CDC.

Wear gloves to reduce the risk of skin irritations, cuts and certain contaminants. Sun protection includes a long-sleeved shirt, a wide-brimmed hat, and sunscreen with sun protective factor (SPF) of 15 or higher, the CDC recommends.

Protect yourself from disease-carrying mosquitoes and ticks by wearing a long-sleeved shirt and tucking your pants in your socks. Rubber boots are a good idea because ticks typically lurk close to the ground. And, use insect repellent with DEET.

When using lawn and garden power equipment, wear safety goggles, hearing protection, sturdy shoes and long pants. Make sure equipment is working properly and sharpen tools carefully. Follow instructions and warning labels when using lawn and garden equipment, and chemicals. Keep chemicals, tools and equipment out of children’s reach.

If it’s a hot day, limit your time in the sun and be sure to drink plenty of water. Take regular breaks and try to rest in shady areas. Stop gardening if you develop shortness of breath or muscle soreness, the CDC advises.

Monitor yourself and others for signs of heat-related illness, such as headache, rapid pulse, dizziness, nausea, confusion, loss of consciousness and extremely high body temperature.

People at higher risk for heat-related illnesses include seniors and children younger than 4 years of age, people who are overweight or have health problems, and those who take certain medications, such as drugs for depression, insomnia or poor circulation, the CDC says.

More information

The U.S. Centers for Disease Control and Prevention has more gardening health and safety tips.





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Take Precautions to Prevent Child Poisonings

FRIDAY, April 22, 2016 (HealthDay News) — From detergents to prescription medication, many common household items can poison children, an emergency medicine physician warns.

Prescription drugs are one of the main threats, said Dr. Wally Ghurabi, medical director of the Nethercutt Emergency Center at the University of California, Los Angeles Medical Center.

Recently, three middle school students were treated in the ER after taking the anti-anxiety drug Xanax they had found at home, Ghurabi said.

“They spent 12 hours in the emergency department having their stomachs pumped and being monitored for adverse reactions,” he said in a medical center news release. “It was serious.”

Drugs intended for adults can be toxic to children, he noted.

“A common medication used to treat diabetes can stay in one’s system for 96 hours — up to four days. While its purpose is to lower an adult’s blood sugar, in a child it can cause glucose to drop to dangerously low levels — and to remain there for days,” Ghurabi said.

Parents and other adults need to keep prescription drugs and other toxic substances — including laundry products, drain cleaners and alcohol — away from children, Ghurabi said.

Most child poisonings occur when parents or caregivers are home but not paying attention, according to the American Academy of Pediatrics. The academy offers these poisoning-prevention tips:

  • Store medicines, cleaning and laundry products, paints/varnishes and pesticides in their original packaging in locked cabinets or containers, out of sight and reach of youngsters. The cabinets should have safety latches that automatically lock when the doors close.
  • Remember that while medicine safety caps are child-resistant, they are not fully childproof. Never call medicine “candy” or any other name that might make it appealing to children.
  • Check the label for dosing instructions every time you give a child medicine. When giving liquid medicines, always use the dosing device that came with the product. Never use a kitchen spoon.
  • Never store poisonous products in food or drink containers.
  • Secure remote controls, key fobs, musical greeting cards and books, and other devices that may contain small batteries that can cause injury if swallowed by children.

More information

The U.S. Centers for Disease Control and Prevention offers more poisoning-prevention tips.





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FDA Proposes Ban on ‘Shock’ Device Used to Curb Self-Harm

FRIDAY, April 22, 2016 (HealthDay News) — Electrical stimulation devices, used to treat self-harming or aggressive behaviors, should be banned, the U.S. Food and Drug Administration said Friday.

The devices pose substantial risks that cannot be eliminated through labeling changes, according to the agency.

These electrical stimulation devices deliver shocks through electrodes attached to the skin in an attempt to condition people to stop hurting themselves or being aggressive.

However, there is evidence that the devices are associated with a number of significant physical and mental health risks. These risks include: depression, anxiety, worsening of self-injury behaviors and post-traumatic stress disorder symptoms, pain, burns, tissue damage and unintended shocks from device malfunctions, the FDA said.

The agency also pointed out that many people treated with these devices have intellectual or developmental disabilities that can impair their ability to consent to the procedure or to say they are suffering pain.

New or updated labeling cannot eliminate these risks, so the FDA has proposed the devices be banned to protect public health. The proposal is open for public comment for 30 days.

“Our primary concern is the safety and well-being of the individuals who are exposed to these devices,” according to Dr. William Maisel. He is acting director of the Office of Device Evaluation in the FDA’s Center for Devices and Radiological Health.

“These devices are dangerous and a risk to public health — and we believe they should not be used,” Maisel said in an FDA news release.

FDA information suggests only one facility in the United States is using these devices — the Judge Rotenberg Educational Center in Canton, Mass. It’s believed the device is currently being used on 45 to 50 patients, according to the news release.

Alternative methods of treating self-injury and aggressive behavior include behavioral therapies, such as positive behavioral support, and medications, according to the FDA.

More information

The National Alliance on Mental Illness has more about self-harm.





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4 Things You Should Know About Clinical Trials

Illustration: Mark Allen Miller

Illustration: Mark Allen Miller

When Mary Elizabeth Williams was diagnosed with stage 4 melanoma, her prognosis was grim. But she came across a clinical trial for immunotherapy—which uses the body’s natural defenses to fight cancer—and was declared cancer-free just three months later. Some may be reluctant to take part in a clinical trial due to some well-known myths. Here, she sets the record straight:

RELATED: Will Immunotherapy Be the End of Cancer?

Myth: “If I get into a clinical trial, I’ll be stuck in a placebo group and won’t be treated.”

Fact: “Only a small number of trials employ placebos as a means of measuring a treatment’s effectiveness,” says Williams. “They are much less common in studies like mine, involving people with serious health conditions such as cancer. In my trial, every patient received the same medication. And when control groups are part of a study, patients in those groups typically still receive treatment (which may be the usual standard of care) throughout the trial.”

Myth: “Clinical trials are a last ditch.”

Fact: “While many trials are open only to patients who are late-stage, or for whom other forms of treatment have been unsuccessful, others are available to patients of varying condition,” Williams explains. “Increasingly, doctors are learning to work with patients to tailor a treatment plan that is best for the individual—including exploring trials.”

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RELATED: Jimmy Carter’s Miraculous Cancer Treatment Worked for Me Too

Myth: “I’ll be locked in even if it doesn’t work or I don’t like the trial.”

Fact: “Both the doctor and the patient can reassess throughout, according to how the patient is feeling and her ability to withstand treatment,” says Williams. “It’s just an option—it’s not jail.”

Myth: “Forget it; there’s nothing going on in research in my small town.”

Fact: “Concerned that trials are available only to people close to big-name hospitals? Research craves variety, and trials are often conducted in cooperation with several facilities at a time,” says Williams. “Mine ultimately involved more than 100 facilities around the world. You can search for recruiting studies based on your condition and location at clinicaltrials.gov.”




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