‘Female Viagra’ Drug Approved By FDA

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The first drug to treat a lack of female sexual desire has been approved by federal authorities.

The drug flibanserin, which has been coined “female Viagra,” was approved Tuesday by the U.S. Food and Drug Administration (FDA). The drug is intended to treat hypoactive sexual desire disorder (HSDD)—a persistent lack of libido—in premenopausal women. The agency had rejected the drug twice in the past.

In June, an advisory panel to the FDA voted 18-6 in favor of approving flibanserin, which is developed by Sprout Pharmaceuticals. Though it’s compared to Viagra, the male drug for erectile dysfunction, flibanserin works in the brain by targeting neurotransmitters thought to play a role in sexual excitement.

The drug’s approval is not without controversy. Critics have expressed concern that the benefits of the drug do not override the side effects, which can include sleepiness and nausea. In clinical trials of the drug, 13% of women stopped taking flibanserin due to side effects. Some critics also take issue with the fact that the drug needs to be taken every day.

“I think it’s a disaster. It’s unsafe and it doesn’t work. That is all a drug is supposed to do,” Leonore Tiefer, clinical associate professor of psychiatry at NYU School of Medicine told TIME.

Other experts argue that though the drug may be imperfect, it gives physicians an option to offer female patients. “Currently, there is no drug available in the U.S. for the treatment of HSDD, and clinicians and patients are very interested in having access to an approved medication,” Dr. Bob Barbieri, chair of the department of obstetrics and gynecology at Brigham and Women’s Hospital told TIME. “Once the drug is available to clinicians and patients, the role of the drug in the treatment of HSDD will be better clarified.”

MORE: Here’s What It’s Like To Take ‘Female Viagra’

The FDA has taken steps to cite possible risks. Due to risks associated with drinking alcohol while taking the drug, the FDA says flibanserin will only be available through specially certified health care professionals and certified pharmacies. The drug will also contain a “boxed warning” that highlights the risk of severe low blood pressure and loss of continuousness among patients who drink alcohol and take flibanserin and other at-risk patients.

Women’s groups that advocated for the drug’s approval under the campaign, Even the Score, framed the issue as sexist, arguing there are 26 approved drugs for sexual dysfunctions among men but none for women. The campaign was backed by Sprout.

Sprout Pharmaceuticals will be selling flibanserin under the brand name ADDYI. You can read more about the FDA decision here.

MORE: What 8 Medical Experts Think About ‘Female Viagra’

This article originally appeared on Time.com.

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How to Properly Apply Bronzer, Once and For All

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Ah bronzer. When used correctly, it can take you to a whole new level, “I just got back from vacation and I’m so healthy and glowing” gorgeous. But, if it goes wrong, it goes so, so wrong. Like, Pig Pen wrong. Not that we don’t love the Peanuts character, but that’s not what we’re aiming for on a day-to-day basis. We broke down the best way to bronze yourself, for your convenience, because we love our MIMI fans and always want you to look your most gorgeous.

Here’s how to get the look:

1. Choose a brush.

2. Apply bronzer along the hairline, temples, cheeks, jawline

3. Blend down your neck.

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MIMI Chatter is an endless stream of beauty content. We bring together the must-knows and the how-tos from your favorite sites, beauty influencers, our editors, and YOU.

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Stop, No! 10 Ways You’re Using Your Clarisonic Totally Wrong

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Dermatologists, beauty editors, and celebrities alike swear by the Clarisonic cleansing brush ($199). We had a chance to talk to Clarisonic cofounder Dr. Robb Akridge and discovered something horrifying . . . we’ve been missing some crucial steps in our daily Clarisonic routine! Sure, we know how to clean it, but these tips will help you get the most out of your favorite skin-care device.

More Means More

You’re not using enough face wash. The first time you use your brush Dr. Robb recommends filling the entire inner circle with cleanser (about a quarter-sized amount). Then, you can adjust accordingly for your skin type.

You’re not using enough water. Just like your toothbrush, you need to thoroughly soak your Clarisonic in water to get the ultimate pore-cleaning action.

You’re sharing your brush head with your boyfriend. First of all — ew. Just no. Even though the Clarisonic doesn’t harbor bacteria, you would be swapping genetic material in an entirely new way. Just get him his own brush head. If he’s already done the deed, soak your brush head in rubbing alcohol for a few seconds.

Customizable Clean

You don’t fine-tune your brush head. As an extra step you can remove the outer ring of the Clarisonic brush head and use the inner circle in that tight crevice around the nose. Just beware of extra splashing!

You don’t clean it with shampoo. Dr. Robb recommends cleansing the Clarisonic after every use with a bit of shampoo to keep the bristles clear of residue and oil.

You stopped using it because of a breakout. Transient acne is a potential side effect for first-time Clarisonic users. The stimulation of the skin can cause bacteria to rise to the surface in the form of a pimple. The solution: Scale back your use to once a day, but keep with it. Things should clear up after about two weeks of continual use.

Deep Cleansing

You don’t clean under the brush head. Once a month remove your brush head and cleanse the well below with soap and water to keep everything squeaky clean.

You use your Clarisonic with an exfoliating cleanser. Double the exfoliation is not a good thing in this case. Avoid any cleansers with microbeads or rough particles.

You don’t replace your brushes every three months. Dr. Robb says it isn’t the bacteria you need to get rid of, it’s more about the efficiency of the machine. Over time the bristles begin to clump together, so a replacement is required!

You don’t restart the cycle for your neck and décolletage. Go ahead and push that button again to give your neck and collarbone a good antiaging scrub.

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POPSUGAR Beauty puts the focus on hair, makeup, nails, and fragrance — from inspiring celebrity photos and fun polls, to easy how-tos to re-create the latest trends at home, to expert tips from the world’s top stylists! Find out the latest color trends for your face, hair, and nails with hot new products and daring nail design ideas. DIY ideas turn your home into a spa, and make you knowledgeable on any beauty topic. Let POPSUGAR Beauty be your guide to all things skin care, makeup, and hair care!

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The Workout That Helped Gina Rodriguez Find Her Inner Strength

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Actress Gina Rodriguez is having quite the year. In January, the Jane the Virgin star won a Golden Globe award for her portrayal of Jane Villanueva, a young woman who’s accidentally inseminated at her gyno’s office when she’s there for a routine pap smear. The comedy-drama doesn’t return to The CW until October 12^th, but Rodriguez has kept busy rolling with the punches—literally. The 31-year-old is an avid boxer. We sat down with Rodriguez to get her advice on punching up, maintaining self-confidence, and staying motivated every single day.

I see on your Instagram how much you love boxing. What inspired you to start?

My dad just retired, but he was a professional referee for boxing. So I grew up in boxing. I was always involved in boxing, but it wasn’t until this summer [that I really got into it]. It was a pretty transformative summer. You know when you have those times in your life when you’re like, “I’m definitely going through a season and things are changing”? I went kind of knee-deep into it, which is nice because then I got closer to my dad, but then I got closer to my inner strength. I would never use boxing to hurt anyone. On the contrary, it just made me feel like I don’t have a victim walk, and I love it. It’s so empowering. And I feel pretty strong.

RELATED: Mix-and-Match Boxing Moves You NEED to Try

Do you do any other workouts?

I’m training to do a marathon with Nike right now, so I will be doing the half-marathon in October in San Francisco. The guy who plays my baby daddy in the show [Justin Baldoni] does documentaries called My Last Days [that follows people living with terminal illnesses], so I will be running in the name of one of the girls that’s in the documentary.

How’s training going?

Oh girl….running is tough. My body is like aye [grabs aching shoulders]. But it’s going to be okay. It’s going to be great. I have two more months.

Do you have any workout playlists that you like?

It’s interesting because I don’t even need pumped-up music. I kind of need soft music. So it’s not like “Get it! Get it!” It’s more like Sam Smith, like Jessie Ware. I will literally be like running and sobbing….It’s totally an emotional journey.

RELATED: The Ultimate Beyoncé Workout Playlist

And I saw that Britney Spears is going to be on your show [in season two].

Oh my god. I’m so frigging excited. I’m so excited.

 

Do you have a favorite Britney song?

Mine is back in the day, her first […Baby One More Time]. I grew up with Britney. To be on a show that she wants to be on and that she desires to come be a part of? I mean, that’s like, someone slap me across the face, that’s not really happening is it? When she’s there I’m going to be like, “Oh my god, it’s you! It’s you!….Can we just do all the dances to every single song? Just teach me all of them, please. Right here in this big warehouse, please.”

Do you have any personal mantras or quotes that you live by?

Today’s going to be a great day. I can and I will.

RELATED: How to Stick to a Workout Plan

How do you maintain your body confidence and self-esteem in Hollywood?

It’s a very difficult thing. I mean it’s definitely an interesting balance because you want to not get swept up in an image that does not exist. [It’s] staying true to who you are; not even who you are in the sense that I’ll never get super thin, or I’ll never get plastic surgery. It’s staying [true] to the comfort of your body, and that’s a personal journey for everyone. To try to look like someone else is impossible. To try to attain something that isn’t meant for your body is impossible.

I think embracing who you are right now is so necessary in an industry that’s constantly telling you you’re not enough. I feel very blessed to have had a foundation of someone that told me time and time again that I was enough, that I am beautiful the way I am today, that as long as I work hard and am good to others, and I keep my integrity and my respect for myself, that I will be okay.

It’s working on me all the time because you’re held accountable for everything you put out, you’re held accountable for everything you do; there [are] no takebacks. So the journey of who you are is where you have to begin. I went on that journey a while ago, and everything happens for a reason I think. Jane came into my life at a time when I was prepared to take on such a responsibility.

Editor’s Note: This interview has been condensed and edited for clarity.

Did you miss the first season of Jane the Virgin? No worries, you can catch up on Hulu. See how Rodriguez describes her character in the clip below.

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Synthetic MERS Vaccine Works in Animal Tests

WEDNESDAY, Aug. 19, 2015 (HealthDay News) — An experimental vaccine protected monkeys against the Middle East Respiratory Syndrome (MERS) virus, U.S. researchers report.

University of Pennsylvania researchers gave the synthetic DNA vaccine to rhesus macaques six weeks before exposing them to the MERS virus, and found that all of them were fully protected.

The vaccine also generated potentially protective antibodies in blood from camels, believed to be the source of MERS transmission in the Middle East.

The study was published Aug. 19 in the journal Science Translational Medicine.

Since it was identified in 2012, the coronavirus has caused more than 1,300 infections and nearly 400 deaths in the Middle East, Europe, South Korea and the United States, the researchers said.

“The significant recent increase in MERS cases, coupled with the lack of effective antiviral therapies or vaccines to treat or prevent this infection, have raised significant concern,” study author David Weiner, a professor of pathology and laboratory medicine at the university’s Perelman School of Medicine, said in a university news release.

“Accordingly, the development of a vaccine for MERS remains a high priority,” he added.

The experimental vaccine is non-live and poses no risk of unintended spread of the virus, study first author Karuppiah Muthumani said in the news release.

Muthumani, a research assistant professor of pathology and laboratory medicine at the Philadelphia-based university, said the vaccine could potentially overcome important production and delivery issues.

More information

The U.S. Centers for Disease Control and Prevention has more about MERS.

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Scientists Probe Obesity’s Ties to Breast Cancer Risk

By Emily Willingham
HealthDay Reporter

WEDNESDAY, Aug. 19, 2015 (HealthDay News) — Obesity is a well-known risk factor for breast cancer, but researchers haven’t figured out what connects the two. A new study suggests the link may be due to a change in breast tissue structure, which might promote breast cells to progress to cancer.

The findings, based on research with tissue from mice and humans, emphasize the need to encourage a healthy weight in women who have breast cancer and in general. The results may also have implications for breast cancer detection and breast reconstruction surgeries, the researchers reported in the Aug. 19 issue of Science Translational Medicine.

The authors of an editorial accompanying the paper said the findings could be key to solving the puzzle of how obesity leads to breast cancer or worsens outcomes for women with the disease. This kind of information could open the way to treatments that target those pathways, according to Lisa Arendt, a research assistant professor, and Charlotte Kuperwasser, an associate professor, at Tufts University in Boston.

“Unfortunately, therapeutics specific for obese women with breast cancer are limited,” Arendt and Kuperwasser wrote. They said that obesity accounts for as much as one-fifth of all cancer deaths among women.

The processes underlying the obesity-breast cancer link had left specialists stumped, although some had proposed obesity-related differences in hormones or inflammation. But obesity-related stiffening of breast tissues was not high on the list.

In the new work, Cornell University doctoral student Bo Ri Seo and colleagues looked at breast fat tissue in humans and mice. They found that in obesity, the web-like network of fibers holding fat cells in place is more rigid than normal.

Curious about whether obesity-related genetics might play a role, the researchers compared tissues of mice that were genetically obese and mice that became obese from overfeeding. Regardless of how they became obese, their tissues still were stiffened, the investigators found.

The researchers also ruled out a common inflammation-related molecule as playing a role. They concluded that the stiff structure itself seemed to be the relevant factor.

To assess that idea further, the study authors also exposed precancerous breast cells to these stiff fibrous networks from obesity-related tissue samples. Cells growing under these conditions were more likely to become completely cancerous compared to those grown in non-obesity-related samples.

Finally, the researchers turned to the obvious question: Would weight loss reduce this stiffening effect?

When the researchers placed obese mice on a diet, the fibrous network thinned out a little, “hinting that weight loss can potentially reverse this tissue stiffening,” the study authors explained in a journal news release.

Another question is how obesity leads to the stiffer tissues. Arendt and Kuperwasser said that low oxygen in the denser tissues might be one explanation. And, they noted, it’s still possible that an inflammatory process plays a role.

Dense breast tissue on a mammogram is associated with a higher probability of developing breast cancer, Seo and her co-authors pointed out. But fat tissue might mask this kind of density, they added, suggesting that for obese women, more focused, high-resolution imaging might be called for to detect hidden areas of density.

The study authors also noted that using donor breast tissue to regenerate breasts after complete breast removal is becoming a possibility. If donor tissue from obese women might carry a risk of promoting cancerous changes in breast cells, that factor may need to be considered, they suggested.

Obesity-related breast cancer rates are likely to increase as obesity rates keep rising, Arendt and Kuperwasser warned. Currently, weight loss is the only recommendation for obesity in women diagnosed with breast cancer.

Diabetic women who take the drug metformin have a lower risk of developing breast cancer. For this reason, this diabetes drug is also being tested in clinical trials as treatment for obesity-associated breast cancer, the editorialists said.

But little research has addressed how weight loss might affect risk for developing breast cancer in the first place. One recent study, Arendt and Kuperwasser wrote, found no effect of short-term weight loss on this risk in postmenopausal women.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about health risks related to obesity.

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Only 1 in 10 With Heart Failure Sent to Rehab Programs

WEDNESDAY, Aug. 19, 2015 (HealthDay News) — Cardiac rehabilitation programs offer many benefits to heart failure patients, but only one in 10 are referred to such programs, a new study reveals.

There is strong evidence that cardiac rehabilitation therapy improves heart failure patients’ quality of life and reduces their risk of hospitalization, the researchers noted. The programs include exercise training, education on heart-healthy living and counseling.

The researchers analyzed data from more than 100,000 heart failure patients in the United States who were discharged from hospitals between 2005 and 2014 and were eligible for cardiac rehabilitation programs.

Overall, slightly more than 10 percent of the patients were referred for rehabilitation when they left the hospital. Referral rates did increase during the study period, but remained low.

Younger patients and men were more likely to be referred for rehabilitation than older patients and women. Those who received referrals were also more likely to be prescribed recommended heart failure medications when they left the hospital.

The study is published in the Aug. 25 issue of the Journal of the American College of Cardiology.

“Although we expected some under-referral to cardiac rehabilitation in the heart failure population, the results of this study are startling,” study senior author Dr. Gregg Fonarow, a professor of cardiology at the University of California, Los Angeles, said in a university news release.

Given the benefits of these programs and the rising costs of hospitalizations, “our findings point to the need for better strategies to increase physicians’ and patients’ awareness about the importance of cardiac rehabilitation,” he added.

Fonarow said doctors who are more likely to incorporate state-of-the-art therapies to manage heart failure patients are also more apt to refer them to rehabilitation programs.

“This suggests that raising awareness about the benefits of these programs may be an effective strategy for increasing referrals,” he said.

Other approaches that may get more patients into rehabilitation include increasing insurance coverage and reducing co-payments for such programs, and expanding the responsibilities of home care nurses, physical therapists and other health care providers for more community-based rehabilitation, the researchers suggested.

More information

The U.S. National Heart, Lung, and Blood Institute has more about cardiac rehabilitation.

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How to Make a Pumpkin Spice Latte at Home

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Let’s free-associate for a minute. If I say “autumn,” and you reply, “pumpkin spice latte,” good news: Your favorite fall beverage just got a health upgrade.

Both Starbucks and Panera Bread both came out with announcements this week that they’re changing up their PSL recipes; both restaurants will now make them with real pumpkin. On top of that, Starbucks says they’ll omit caramel coloring, while Panera will serve drinks made “entirely without artificial colors, flavors, sweeteners, preservatives or high-fructose corn syrup,” The Associated Press reports.

That’s certainly a plus, no matter which you prefer. But we decided to go one better, and give you a pumpkin spice latte that you can enjoy any time of year—at home. Plus, when you make your own, you control the level of sweetness and spice and whether to use organic ingredients. Plug in that blender and get ready to sip your way to pumpkin perfection.

Healthier Pumpkin Spice Latte

Serves: 1

2 Tbsp. canned pumpkin puree
½ tsp. pumpkin pie spice (or ¼ tsp. cinnamon and 1/8 tsp. each ground nutmeg and ground ginger)
Pinch of salt
1 tsp. vanilla extract
1/2 cup milk of choice (I use homemade cashew milk)
1 cup hot, strongly brewed coffee
1 to 2 tsp. raw honey (or more to taste, if desired)
1 Tbsp. unsalted grass-fed butter (such as Kerrygold) or coconut oil, optional

In a saucepan over medium-low heat, combine pumpkin, pumpkin pie spice and salt and cook, stirring, until warmed and fragrant, about 2 minutes. Whisk in vanilla and milk and cook, whisking, until warmed through, 1 to 2 minutes.

Transfer pumpkin mixture to a high-speed blender and add coffee, honey and butter, if desired. Blend until well mixed and frothy. Drink immediately.

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Black Women Less Likely to Survive Uterine Cancer, Study Finds

WEDNESDAY, Aug. 19, 2015 (HealthDay News) — Uterine cancer rates are rising in the United States, particularly among black and Asian women, according to a new study that also found black women are more likely to die of the disease.

Researchers analyzed more than 120,000 cases of uterine cancer diagnosed in the United States between 2000 and 2011, and found that rates rose among all racial and ethnic groups. But rates increased fastest, at 2.5 percent a year, among black and Asian women.

Black women also had higher rates of aggressive uterine cancer than Asian, Hispanic and white women, and death rates for aggressive uterine cancer were more than 1.5 times higher among black women than among white women.

Death rates for aggressive uterine cancer were similar or lower among Asian and Hispanic women, compared to white women.

A five-year analysis found that black women had poorer survival rates than white women at every stage of diagnosis. Five-year survival rates among Asian and Hispanic women were similar or higher, compared with white women.

The study was published Aug. 19 in the journal Cancer Epidemiology, Biomarkers & Prevention.

Study author Michele Cote said in a journal news release that the data suggest that differences in patients’ outcomes persist even when the type of tumor and its stage at diagnosis are accounted for. Cote is associate professor of oncology at the Barbara Ann Karmanos Cancer Institute and Wayne State University School of Medicine in Detroit.

“It was somewhat surprising that the [uterine] cancer survival disparity we identified was limited to non-Hispanic black women, because many of the challenges previously linked to worse outcomes, including low socioeconomic status and high rates of obesity and diabetes, are also experienced by Hispanic women, but that population did not have poor outcomes,” she said.

Cote said researchers are interested in investigating whether there are molecular differences in tumors from women of different races or ethnicities who are diagnosed at the same stage of disease.

More information

The U.S. Office on Women’s Health has more on uterine cancer.

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Insulin Pumps Nearly Halve Risk of Heart Disease Death for Type 1 Diabetics

By Serena Gordon
HealthDay Reporter

WEDNESDAY, Aug. 19, 2015 (HealthDay News) — People with type 1 diabetes who use insulin pumps seem to have a much lower risk of dying from heart disease or stroke prematurely than those who rely on multiple daily injections of insulin, new research suggests.

“As done in Sweden at the time of this study, insulin pump treatment almost halved cardiovascular mortality,” said study author Dr. Isabelle Steineck, from Aarhus University Hospital in Denmark.

The researchers found a 45 percent lower risk of dying from heart disease early for insulin pump users. And the risk of dying early from heart disease or stroke was 42 percent lower for insulin pump users, while the risk of all-cause death was 27 percent lower during the seven-year study period.

Because this was only an observational study, the authors can’t say for sure that insulin pumps lowered death risk during the study, although they did find a significant association between these factors.

The findings were published recently in the BMJ. No funding for the study was provided by insulin pump manufacturers, Steineck added.

Type 1 diabetes is a disease that causes the body’s immune system to mistakenly attack the insulin-producing cells in the pancreas. Insulin is a hormone that helps the body convert sugar from foods into fuel. People with type 1 diabetes must replace that lost insulin to survive.

There are two basic ways to do this. One is multiple daily injections of insulin. The second option is an insulin pump. An insulin pump delivers insulin through a tiny tube that’s inserted under the skin. The person with diabetes programs the pump to tell it how much insulin to deliver and when. Insulin pumps are not fully automated; they still require a lot of input from the person using the pump, the study authors explained.

Type 1 diabetes increases the risk of heart disease and stroke. The risk of dying from heart disease is twice as high for someone with type 1 diabetes compared to someone in the general population, the study authors said.

The study included more than 18,000 people with type 1 diabetes from the Swedish National Diabetes Register. Nearly 2,500 of them used an insulin pump to manage their diabetes, the study said.

Pump users’ average age was 38; for those taking injections, it was 41. During an average of almost seven years of follow-up, nearly 1,200 people died, the study found.

Steineck noted that insulin pumps and their supplies are fully covered by insurance in Sweden, although the choice of pumps is limited.

So how might insulin pumps reduce the risk of premature death? It’s possible they reduce the number of severe episodes of low blood sugar levels (hypoglycemia), the study authors suggested. Hypoglycemia has been linked to heart disease risk, they said.

It’s also possible that the additional education received when switching from injections to an insulin pump may help patients better manage their blood sugar levels, Steineck noted.

“We evaluated the patients who used insulin pump therapy and do not know if the observed effect is attributable to continuous infusion of insulin or that some, if not all, of the effect is attributable to intensified glucose monitoring, increased motivation to control blood glucose, or a better knowledge about having type 1 diabetes,” she explained.

One expert said the findings were interesting, but not conclusive.

“Continuous insulin infusion, otherwise known as pump therapy, is a more physiologic approach that has been shown in many analyses to be beneficial,” said Vincent Crabtree, director of research business development for JDRF (formerly the Juvenile Diabetes Research Association). “This paper is intriguing, but will need more research to draw definitive conclusions.”

Crabtree said that fewer than half of Americans with type 1 diabetes use an insulin pump.

Steineck hopes this new study will help boost those numbers. “Our study is one of many that gives evidence for a greater insurance coverage for insulin pumps,” she added.

More information

Learn more about insulin pumps from the American Diabetes Association.

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