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Younger Women With Diabetes More Vulnerable to Heart Attack: Study

WEDNESDAY, Sept. 2, 2015 (HealthDay News) — Young women with diabetes are much more likely to have a heart attack than those without the blood sugar disease, new research says.

The study from Poland also found that young women who actually had a heart attack were more likely to be smokers than older women who had suffered heart attacks.

To reach these conclusions, the researchers looked at nearly 7,400 Polish women. Among those aged 45 and younger, women with diabetes were six times more likely to have a heart attack than those without diabetes.

High blood pressure increased the risk by four times, high cholesterol levels tripled the risk and smoking nearly doubled the risk. There was no significant link between obesity and heart attack risk, but this may be due to the fact that diabetes was so common among obese young women, according to study co-author Hanna Szwed, a professor at the Institute of Cardiology in Warsaw.

The study was presented Monday at the European Society of Cardiology annual meeting in London. Research presented at meetings is considered preliminary until published in a peer-reviewed medical journal.

“We found that the risk factor profile in young women with [heart attack] was similar to the older population, apart from the greater occurrence of tobacco smoking in young women,” Szwed said in a society news release.

“This finding correlates with other research which shows that smoking is a growing problem in young women. This is clearly an area where prevention efforts are needed,” she added.

“At present there are not enough global scientific reports focused on the problem of coronary heart disease in young populations, particularly in women,” Szwed said.

More research is needed to improve public health efforts to fight heart disease in this age group, Szwed concluded.

More information

The U.S. National Heart, Lung, and Blood Institute has more about women and heart disease.





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More Men With Breast Cancer Having Second Breast Removed

WEDNESDAY, Sept. 2, 2015 (HealthDay News) — There has been sharp rise in the number of American men with cancer in one breast who have surgery to remove their cancer-free breast, a new study said.

The study authors said this is the first research to identify this trend in men, which has been occurring in American women for the past two decades.

“The increase in the rate of this costly, serious procedure with no evidence of survival benefit comes, paradoxically, at a time of greater emphasis on quality and value in cancer care,” said study leader Dr. Ahmedin Jemal, vice president of surveillance and health services research at the American Cancer Society.

The study included more than 6,300 men who had surgery for cancer in one breast. Their surgeries occurred between 2004 and 2011. The percentage of men who also had their cancer-free breast removed rose from 3 percent in 2004 to 5.6 percent in 2011, the study found.

Those mostly likely to have their cancer-free breast removed were younger, white and privately insured, the study said.

Findings were published online Sept. 2 in the journal JAMA Surgery.

“Health care providers should be aware that the increase we’ve seen in removal of the unaffected breast is not limited to women, and doctors should carefully discuss with their male patients the benefits, harms and costs of this surgery to help patients make informed decisions about their treatments,” Jemal said in a journal news release.

Men account for only about 1 percent of breast cancer patients in the United States.

The percentage of women with invasive breast cancer in one breast who have their cancer-free breast removed rose from 2 percent in 1998 to 11 percent in 2011. This, despite the risk of complications and a lack of evidence that it improves the chances of survival, according to background information from the study.

More information

The U.S. National Cancer Institute has more about male breast cancer.





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More Americans Getting Knees Replaced, And at Younger Ages

WEDNESDAY, Sept. 2, 2015 (HealthDay News) — Aging baby boomers are getting bum knees replaced at a greater rate, and at a younger age, than ever before, a new U.S. study confirms.

The data, from the National Hospital Discharge Survey, shows that between 2000 and 2010, more than 5.2 million total knee replacements were performed in the United States. By 2010, the operation had become the leading inpatient surgery performed on adults aged 45 and over.

The rate at which middle-aged and older Americans got their knees replaced almost doubled over the years covered by the study, for men and women, the researchers found.

People aren’t putting off the procedure for as long, either. In 2000, the average knee replacement patient was about 69 years old, but by 2010 that age had dropped to just over 66, the findings showed.

One expert said there’s been a change in doctors’ and patients’ attitudes toward the timing of knee replacement.

“In the past, the trend amongst orthopedic surgeons was to delay performing a joint replacement on a patient until a person was so hindered by their joint pain that they were nearly incapacitated in their activities of daily living,” said Dr. Neil Roth, an orthopedic surgeon at Lenox Hill Hospital in New York City.

However, “that philosophy has evolved,” he said, so that nowadays surgeons “perform joint replacements sooner, to prevent physical deterioration and deconditioning, and to try to maintain activity levels.”

The new study was led by Sonja Williams of the U.S. Centers for Disease Control and Prevention’s National Center for Health Statistics (NCHS) and published in the September issue of the NCHS Data Brief.

Looking over the data, her team also noted a gender gap in knee replacement rates, with women significantly more likely to get a new knee compared to men. In 2010, about 65 of every 10,000 women aged 45 or older got a knee replacement, the research showed, compared to about 45 of every 10,000 men of similar age.

Why is the operation becoming more popular for both genders? According to Roth, aging boomers are demanding more mobility as they age.

“People want to remain active longer, well into their 8th and 9th decades of life, and painful joints are not conducive to remaining active,” he said.

Joint replacements are getting better, too, he added.

“Technologically, the longevity of knee and hip implants has also improved, lasting sometimes up to 15 years or longer,” Roth said. “While that still may necessitate revision surgery for those patients in the younger age groups, 45 to 64, it may not require two revision surgeries.”

Also, “the surgeries are more sophisticated now,” Roth said, “especially with the use of [surgical] navigational systems, as well as custom-made knee and hip replacements.”

The bottom line, he said, is that “all of these factors have led to an increased utilization of joint replacements for those needing them at an earlier age and has put aside the mantra of ‘waiting until you can’t take it any longer.'”

Roth stressed that these procedures remain invasive and complex, are not without risk, and shouldn’t be taken lightly. “Joint replacement surgery is still a major surgical procedure with significant risks, such as blood clots, infection and loss of motion,” he said.

Dr. Eric Grossman is co-director of joint replacement surgery at Northern Westchester Hospital in Mount Kisco, N.Y. He agreed that the rise in joint replacement has largely been based on patient demand.

“Patients today are unyielding in their desire to continue to be active and maintain a physically vivacious life,” Grossman said. “For patients with severe, debilitating arthritis, a total knee replacement can reliably achieve significant improvements in a patient’s pain and functional level, including returning to walking, cycling, tennis, golf, and skiing among other activities.”

And there’s been one other improvement boosting uptake of the operation, he added.

“Hospital lengths of stay continue to decline as refinement of the rehabilitation is also improved,” Grossman said. “Patients used to be hospitalized for weeks. In some cases today the surgery is being done on an ambulatory basis, but most commonly patients stay in the hospital for just one to three nights.”

More information

Find out more about knee replacement at the American Academy of Orthopaedic Surgeons.





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Lipliners You Can Use With Any Lipstick

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Whether or not you’re into over-lining your lips à la Kylie Jenner, the right lip liner is a necessity. But, because we have so many lipsticks, it’s impossible to purchase a matching lip liner for each shade. That is, unless you have your own glam room like a Kardashian.

Enter: Nude and clear lip liners. These babies will eliminate bleeding and prolong the wear of your color—and theyalways match. Just like your imaginary childhood best friend, but REAL. Too far? OK. All you need to do is trace around your lip line before you apply your preferred shade. Or, you can apply all over your pout as a base to make sure it lasts all day… and night.

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1. Chantecaille Lip Definer Pencil in Natural, $24; barneys.com

2. Sisley Paris Perfect Lipliner #1 in Nude, $57; barneys.com

3. Lipstick Queen Invisible Lip Liner, $18; netaporter.com

4. Becca Nude Liner Plump & Define Lip Pencil, $23; sephora.com

5. The Body Shop Lip Liner in Nude, $10.50; thebodyshop.com

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6. e.l.f. Studio Lip Lock Pencil, $3; eyeslipsface.com

7. Merle Norman Clear Lip Pencil, $14; merlenorman.com

8. Sephora Collection Universal Lip Liner, $10; sephora.com

9. Urban Decay 24/7 Glide-On Lip Pencil in Ozone, $20; sephora.com

10. Too Faced Perfect Lips Lip Liner in Perfect Nude, $17; ulta.com

This article originally appeared on MIMIchatter.com.

popsugarblack_small.jpg MIMI Chatter is an endless stream of beauty content. We bring together the must-knows and the how-tos from your favorite sites, beauty influencers, our editors, and YOU.



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Acupuncture Might Help Ease High Blood Pressure

By Randy Dotinga
HealthDay Reporter

WEDNESDAY, Sept. 2, 2015 (HealthDay News) — Can acupuncture benefit people with mildly or moderately elevated blood pressure?

Perhaps, a small study suggests, but the researchers behind the trial acknowledge that it’s too soon to say for sure.

The researchers found that blood pressure levels declined slightly in a small group of patients treated 30 minutes a week with “electroacupuncture” — where the needles carry low-level electrical stimulation — at specific points of the body.

“Potentially, blood pressure can be kept low with a monthly follow-up treatment,” said study co-author Dr. John Longhurst, a cardiologist at the University of California, Irvine.

An estimated 70 million U.S. adults — one in three — have high blood pressure, according to the U.S. Centers for Disease Control and Prevention. It’s believed that only half have their condition under control. High blood pressure can lead to stroke and heart disease.

Blood pressure can often be lowered by becoming more fit, taking medications or both. But these approaches don’t work for everyone, and medication can cause side effects, especially among the elderly.

Acupuncture, an ancient Chinese therapy, is increasingly viewed as a possible alternative, the researchers said in background notes with the study. Practitioners insert thin needles into key points on the body in an attempt to rebalance the flow of energy.

Because previous studies on acupuncture’s effect on high blood pressure have had mixed results, the researchers set out to explore the subject more thoroughly. They compared electroacupuncture at two sets of points in their study of 65 high blood pressure patients.

High blood pressure was defined as 140-180 mm Hg over 90-99 mm Hg. None of the participants was taking blood pressure medication.

Normal blood pressure is defined as 119/79 or lower, according to the U.S. Institutes of Health.

Patients were randomly assigned to one of two types of acupuncture for eight weeks. One type targeted the inner wrists and legs below the knee — points shown to potentially lower blood pressure in previous research. The other technique involved the forearm and lower leg and resulted in no blood pressure improvement, the researchers said.

“A noticeable drop in blood pressure was observed in 70 percent of the patients treated at the effective points, an average of 6 to 8 mm Hg for systolic blood pressure [the top number] and 4 mm Hg for diastolic blood pressure [the lower number],” Longhurst said.

These changes were considered slow and long-lasting — persisting for about six weeks, the study found.

The researchers also found that blood pressure readings dipped further in a group of “high responders” that underwent monthly treatment for six more months.

Exactly how acupuncture might improve blood pressure isn’t clear. Longhurst said it’s possible that stimulation of the affected nerves stimulates areas of the brain that control blood pressure.

In some cases, he said, insurance might cover the alternative treatment, which can cost $60 to $120 per visit.

Longhurst acknowledged that the research doesn’t address whether acupuncture could help patients already taking blood pressure medication.

Dr. Randall Zusman, director of the division of hypertension at Massachusetts General Hospital Heart Center, said the study leaves several questions unanswered.

Zusman said the study doesn’t include enough information about the participants and their blood pressure history. It’s not clear, for example, how recently they took medication, if they did. And he thought the variation in blood pressure among participants was too great. A smaller range would have provided more useful results, said Zusman, who has studied acupuncture.

Still, “the outcomes are interesting and exciting,” he said, “and I’m encouraged that it might have been effective.”

So what should you do if you have high blood pressure?

Zusman said consider modifying your lifestyle, using medication and trying strategies such as relaxation training. Acupuncture is a low-risk procedure, and it could be useful, too, he said.

Longhurst said further studies on acupuncture’s potential for high blood pressure are warranted. But, no additional research is planned, he said, because it’s difficult to find funding.

The study was published recently in the journal Medical Acupuncture.

More information

For more about blood pressure, visit the U.S. National Heart, Lung, and Blood Institute.





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Heart Doctors May Have Hard Time Spotting Valve Problems

TUESDAY, Sept. 1, 2015 (HealthDay News) — Heart specialists can’t always identify heart valve problems through the sound of heart murmurs, but additional training improves their abilities, a new study shows.

A heart murmur is an extra or unusual sound that occurs during a heartbeat, according to the U.S. National Heart, Lung, and Blood Institute (NHLBI). Some murmurs don’t indicate a problem, but others can signal heart valve problems, the NHLBI says.

The study included nearly 1,100 cardiologists who had their skills assessed at American College of Cardiology meetings from 2011 to 2014.

They were asked to diagnose heart valve problems after listening to recordings of heart murmurs. The doctors failed to identify half of basic problems and one-third of advanced problems, the study found.

The cardiologists then did extra training for both basic and advanced heart valve problems (90 minutes each). They improved from 48 percent to 88 percent in identifying basic problems and from 66 percent to 93 percent in identifying advanced problems, the research showed.

The study was presented at a European Society of Cardiology recent meeting in London. Findings presented at meetings are generally considered preliminary until they’ve been published in a peer-reviewed journal.

The study confirms the widely held belief that cardiologists’ skills in identifying heart valve problems have decreased over time, according to study co-author Patrick O’Gara, past-president of the American College of Cardiology.

“As shown in this and other studies, however, these skills can improve with repetition and training,” he said in a college news release.

More information

The American Heart Association has more about heart valve problems.





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Serena Williams to Body-Shaming Critics: ‘I Have Grand Slams to Win’

Credit: Getty Images

Credit: Getty Images

Is there a better athlete alive than Serena Williams? The 33-year-old swiftly took down every one of her opponents this year to win Wimbledon, the French Open, and the Australian Open. And certainly thanks to her, tickets to the U.S. Open women’s final sold out before the men’s for the first time ever, as she attempts to become the first woman to win a single-season Grand Slam since 1988.

Yet somehow, there are people out there focusing on Williams’ appearance instead of her killer skills on the court. But, as she explained on Good Morning America on Monday, she doesn’t let those comments get to her.

“This is me and I love me, and I’ve learned to love me,” Serena told Robin Roberts in a candid interview. “I’ve been like this my whole life, and I embrace me.”

RELATED: Get Toned With Tennis

“And I love how I look. I love that I’m a full woman, and I’m strong and I’m powerful and I’m beautiful at the same time, and there’s nothing wrong with that,” she added.

After she won Wimbledon back in July, the internet trolls came out when J.K. Rowling posted a photo with the tennis superstar. A Twitter user responded to the image adding that Serena is “built like a man,” and Rowling quickly posted an epic comeback, adding, “Yeah, my husband looks just like this in a dress. You’re an idiot.”

RELATED: Get Fit With a Tennis Ball

Williams, meanwhile, doesn’t bother giving the haters an ounce of her time.

“It’s so important to look at the positives,” she told Roberts. “If I get caught up looking at the negatives it could really bring you down, and I don’t have time to be brought down. I have too many things to do. I have grand slams to win and people to inspire and that’s what I’m here for.”

RELATED: 3 Ace Tennis Outfits You’ll Love




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Dentists Drill Patients for Drug Abuse Information

TUESDAY, Sept. 1, 2015 (HealthDay News) — Don’t be surprised if your next dental checkup includes questions about illicit drug use.

A new survey has found that more than three out of every four U.S. dentists ask their patients about illegal drug use.

The poll also found that more than half of dentists believe they should conduct drug screening of new patients.

More than 1,200 dentists nationwide responded to the survey. The researchers found that dentists who believed it was their role to conduct such screenings were much more likely to do so than dentists who didn’t think it was their responsibility.

Why should dentists conduct these screenings?

One reason is that illegal drug use can cause significant dental problems, such as tooth decay, accelerated tooth wear, gum disease and tooth loss, the researchers noted. Another reason is that dentists are the second-largest group of prescribers of powerful narcotic pain medicines called opioids, such as hydrocodone (Vicodin) and oxycodone (OxyContin, Percocet).

“Because dental care routinely involves treating pain and emergencies, dentists may encounter substance-seeking patients who complain of pain more severe than anticipated based on the nature of their dental condition, who report lost prescriptions for opioid pain medications, or who only seek dental treatment sporadically,” lead author Carrigan Parish, an associate research scientist from Columbia University Mailman School of Public Health in New York City, said in a university news release.

The survey found that older dentists were less likely to screen for drug use. Dentists younger than 53 were more likely than older dentists to believe that it was their role to conduct drug screening, 62 percent vs. 47 percent, the study noted.

Female respondents were more likely than males to agree that dentists should screen for illegal drug use, the findings revealed.

Survey results were published online recently in the journal Addiction.

“There are a sizeable number of people whose visit to a dentist represents their sole interaction with the health care system, highlighting the significance of the dental visit as a key opportunity to identify substance use disorders,” Parish said.

“However, our findings underscore a significant barrier in dentists’ attitudes that may limit the potential of the dental venue to play a role in screening for substance misuse,” Parish added.

Parish also said some dentists may require extra training to increase their awareness and knowledge of substance abuse.

What isn’t clear from this study is how dental patients might feel about these screenings.

“While surveys have shown that patients are amenable to receiving medical screenings by dentists ‘chair-side’ for such conditions as HIV, heart disease, and diabetes, further studies directly addressing patient attitudes on substance misuse screening are key in determining patients’ acceptance of such services,” Parish said.

More information

The U.S. National Institute on Drug Abuse has more about drug abuse and addiction.





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Impotence Drug May Help Fight Rare Lung Disease: Study

By Dennis Thompson
HealthDay Reporter

WEDNESDAY, Aug. 26, 2015 (HealthDay News) — A combination treatment that includes the active ingredient in the erectile dysfunction drug Cialis may reduce death and hospitalization from an incurable lung disease that mainly affects women, a new clinical trial shows.

When combined with a blood pressure medication called ambrisentan (Letairis), a high dosage of tadalafil (Adcirca) significantly reduced the progression of pulmonary arterial hypertension, according to results published in the Aug. 27 issue of the New England Journal of Medicine. The condition involves high blood pressure in the arteries leading into the lungs.

Patients who took the combination therapy were half as likely to die, require hospitalization or have severe progression of their illness, when compared with people who only received one of the two drugs, researchers found. People using tadalafil for pulmonary arterial hypertension take 40 milligrams (mg) a day, while the dosage for erectile dysfunction runs between 2.5 mg and 20 mg a day.

The results were so encouraging that the marketer of ambrisentan in the United States has submitted a request to the U.S. Food and Drug Administration so this combination use can be added to the drug’s label, said senior study author Dr. Lewis Rubin, an emeritus professor of medicine at the University of California, San Diego School of Medicine.

Dr. Carl Pepine, past president of the American College of Cardiology, said the results “offer an easy-to-use additional treatment for patients who have this unfortunate condition, who are largely women.”

The two drugs work in different ways to ease the effects of pulmonary arterial hypertension, so researchers decided to see if their impact would be greater used in tandem, Rubin explained.

“This is a complex disease. There’s no magic bullet,” Rubin said. “We postulated that the more pathways you target, the better the effect would be.”

Pulmonary arterial hypertension causes people to be chronically short of breath, as their blood has difficulty getting through the lungs to pick up oxygen. It eventually leads to heart failure because the heart has to pump harder to keep blood circulating through the body.

Pulmonary arterial hypertension is relatively rare, Rubin said, affecting about 50,000 people in the United States. Average survival is roughly two years following diagnosis.

Tadalafil works by blocking PDE5, an enzyme that breaks down a substance called nitric oxide that promotes dilation of blood vessels. With more nitric oxide available, the arteries feeding the lungs are better able to dilate, increasing blood flow.

Ambrisentan works by inhibiting endothelin, a substance that causes blood vessels to constrict, Rubin said. Thus, one drug promotes dilation of blood vessels while the other works to prevent constriction.

Researchers recruited 500 people with pulmonary arterial hypertension to take part in the clinical trial. The study involved 120 medical centers in 14 countries, and ran between October 2010 and July 2014.

About half of the study participants received both drugs, while one-quarter received the high dose of tadalafil alone and another quarter received ambrisentan alone.

Only about 18 percent of people on combination therapy died or experienced severe progression of pulmonary arterial hypertension, compared with 31 percent of people taking either ambrisentan or tadalafil alone, the study found.

And it appeared that using the two drugs together produced no additional side effects, Rubin and Pepine said.

“I was impressed with the relatively good tolerability,” said Pepine, director emeritus of the cardiovascular medicine division at the University of Florida College of Medicine in Gainesville. “I think that will encourage us to use this combination treatment earlier in the course of the disease. It’s possible we might be able to prevent these women from emerging into a very symptomatic stage, where their daily activities are greatly impaired.”

The men taking the combination therapy also might derive other benefits from the tadalafil, given that the dosing is higher for pulmonary arterial hypertension than it is for erectile dysfunction, Rubin said.

“These are sick patients. It’s not uncommon for the men to have erectile dysfunction because they’re sick. Clearly, some of them are deriving some off-target benefits, if you will,” Rubin said. “But their main focus is they can’t breathe and their heart is giving out.”

The clinical trial was funded by Gilead Sciences and GlaxoSmithKline, which sell ambrisentan in the United States and Europe, respectively.

More information

For more on pulmonary arterial hypertension, visit the American Lung Association.





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Cutting-Edge Gene Tests May Improve Management of Autism

By Dennis Thompson
HealthDay Reporter

TUESDAY, Sept. 1, 2015 (HealthDay News) — A pair of genetic tests could help parents and doctors better understand the numerous challenges that a child newly diagnosed with autism might face throughout life, a new study suggests.

The tests tracked down genes that could explain the nature of a child’s autism susceptibility in nearly 16 percent of cases, according to findings published Sept. 1 in the Journal of the American Medical Association.

That number increased to almost 38 percent when researchers used the cutting-edge tests to assess children with certain physical abnormalities. These birth defects are an indication that those children had suffered developmental problems stretching back to the womb, said senior study author Dr. Bridget Fernandez, chair of genetic medicine at Memorial University of Newfoundland in Canada.

Fernandez and her colleagues anticipate that genetic testing of children with autism will continue to increase. She and some other experts believe that, based on the study results, doctors should encourage these tests for kids who show physical signs of developmental problems.

Doctors may be better able to care for children with autism using these tests, because they will have a basic genetic understanding of the kid’s condition, Fernandez said.

For example, the genes linked to a child’s autism might predispose them to obesity or diabetes.

Another autism-linked gene can make children much more prone to seizures, said Mathew Pletcher, vice president and head of genomic discovery for Autism Speaks.

“With that knowledge, now you can start to plan for, prescribe for and treat for those [pending] health issues,” Pletcher added.

The two genetic tests are called chromosomal microarray analysis and whole-exome sequencing. “They are two very comprehensive tests that haven’t been around for too long,” Fernandez said.

Chromosomal microarray analysis identifies abnormalities in a person’s chromosomes, and already is recommended as a first-tier genetic test for people with autism, the researchers said in background notes.

Whole-exome sequencing examines the protein-encoding parts of all of someone’s genes, to look for potential disease-causing anomalies. This test is used mainly in a research setting, Fernandez explained.

It’s estimated that one in 68 American children is on the autism spectrum. The term refers to a group of complex disorders of brain development.

To examine the tests’ potential, the research team used them to assess 258 unrelated children diagnosed with autism spectrum disorder. Their average age was 4.5 years.

Separately, each test was able to track potential genetic causes of autism about equally — about 9 percent for chromosomal microarray analysis and more than 8 percent for whole-exome sequencing.

But the combined tests were effective almost 16 percent of the time. And that effectiveness more than doubled when assessing kids with subtle physical signs of developmental problems, such as differences in the creases on a palm or an oddly shaped ear, the researchers said.

Fernandez expects that the effectiveness of the tests will increase over time, as researchers identify more genes related to autism. “There are still things out there that we don’t know to look for,” she said.

She hopes that knowledge of the genetics behind autism will lead to medications that target those particular faulty genetic pathways. In that case, these tests could help doctors prescribe appropriately targeted drugs to autistic children.

Years down the line, the tests might also be useful in screening siblings of children diagnosed with autism, to see whether they might develop problems related to autism, she said.

But at this point “the tests aren’t cheap,” Fernandez said. Whole-exome sequencing can run from $3,000 to $5,000, while chromosomal microarray analysis costs about $1,500, she said.

Despite this, the tests are so useful that parents of an autistic child should consider them even if their child underwent a genetic exam years ago, said Dr. Judith Miles, a professor emerita of child health genetics at the University of Missouri’s Thompson Center for Autism and Neurodevelopmental Disorders.

“Things have changed,” Miles said. “Families who were evaluated a while ago, it’s very reasonable to come back and allow us to have another look. These tests give you a more specific diagnosis that lets us personalize the care.”

More information

For more on autism and genetics, visit Autism Speaks.





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